16. “Computational Design of Peptides that Target Transmembrane Helices”, Yin, H.; Slusky, J. S; Berger, B. W.; Walters, R. S.; Vilaire, G.; Litvinov, R. I.; Lear, J. D.; Caputo, G. A.; Bennett, J. S.; DeGrado, W. F.; Science 2007, 315, 1817-1822. [Full Text] [C&E News][Faculty of 1000]

15. “The Leech Product Saratin is a Potent Inhibitor of Platelet Integrin Alpha₂Beta₁ and von Willebrand Factor Binding to Collagen”, White, T. C.; Berny, M. A.; Robinson, D. K.; Yin, H.; DeGrado, W. F.; Hanson, S. R.; McCarty, O. J. T.; FEBS J. 2007, 274, 1481-1491. [Link]

14. “Protein Secondary Structure Mimetics as Modulators of Protein-Protein and Protein-Ligand Interactions” in Chemical Biology: From Small Molecules to System Biology and Drug Design (Schreiber, S. L.; Kapoor, T. M.; Wess, G. Ed.), Yin, H.; Hamilton, A. D.; Wiley-VCH Verlag GmbH & Co. KGaA (Weinheim), 2007, 1, Chapter 4.3.

13. “Alpha-Helix Mimetics in Drug Discovery” in Drug Discovery Research: New Frontiers in the Post-Genomic Era (Huang, Z. W. Ed.), Yin, H.; Lee, G. I.; Hamilton, A. D.; John Wiley & Sons (New York), 2007, Chapter 11: 281-299.

12. “Activation of Platelet Alpha_IIbBeta₃ by Exogenous Peptides Corresponding to the Transmembrane Domains of Alpha_IIb”, Yin, H.; Litvinov, R. I.; Vilaire, G.; Zhu, H.; Li, W.; Caputo, G. A.; Moore, D. T.; Lear, J. D.; Weisel, J. W.; DeGrado, W. F.; Bennett, J. S.; J. Biol. Chem. 2006, 281, 36732-36741. [Link]

11. “Arylamide-Based Antagonists that Disrupt the Integrin Alpha₂Beta₁-Collagen Interaction”, Yin, H.; Gerlach, L. O.; Miller, M. W.; Moore, D. T.; Liu, D. H.; Vilaire, G.; Bennett, J. S.; DeGrado, W. F.; Bioorg. Med. Chem. Lett. 2006, 16, 3380-3382. [Link]

10. “Arylamide Derivatives as Peptidomimetic Inhibitors of Calmodulin”, Yin, H.; Frederick, K. K.; Liu, D. H.; Wand, A. J.; DeGrado, W. F.; Org. Lett. 2006, 8, 223-225. [Link]

9. “Terphenyl-Based Alpha-Helical Proteomimetics as Low-Molecular-Weight Antagonists of Bcl-x_L”, Yin, H.; Lee, G. I.; Sedey, K. A.; Kutzki, O.; Park, H. S.; Orner, B. P.; Ernst, J. T.; Wang, H. G.; Sebti, S. M.; Hamilton, A. D.; J. Am. Chem. Soc. 2005, 127, 10191-10196. [Link] [Faculty of 1000]

8. “Strategies of Targeting Protein-Protein Interactions Using Synthetic Agents”, Yin, H.; Hamilton, A. D.; Angew. Chem. Int. Edit. 2005, 44, 4130-4163. [Link]

7. “Terphenyl Derivatives as Alpha-Helical Mimetics of P53”, Yin, H.; Lee, G. I.; Park, H. Y.; Rodriguez, J. M.; Payne, G. J.; Sebti, S. M.; Hamilton, A. D.; Angew. Chem. Int. Edit. 2005, 44, 2704-2707. [Link]

6. “Terephthalamide Derivatives as Mimetics of Helical Peptides: Disruption of the Bcl-x_L/Bak Interaction”, Yin, H.; Lee, G. I.; Sedey, K. A.; Rodriguez, J. M.; Wang, H. M.; Sebti, S. M.; Hamilton, A. D.; J. Am. Chem. Soc. 2005, 127, 5463-5468. [Link]

5. “p53 Alpha-Helix Mimetics Antagonize P53/MDM2 Interaction and Activate P53”, Chen, L. H.; Yin, H.; Farooqi, B.; Sebti, S. M.; Hamilton, A. D.; Chen, J. D.; Mol. Cancer Ther. 2005, 4, 1019-1025. [Link]

4. “Terephthalamide Derivatives as Mimetics of the Helical Region of Bak Peptide Target Bcl-x_L Protein”, Yin, H.; Hamilton, A. D.; Bioorg. Med. Chem. Lett. 2004, 14, 1375-1379. [Link]

3. “Geranylgeranyltransferase I Inhibitor, GGTI-2154, Induces Breast Carcinoma Apoptosis and Tumor Regression in H-Ras Transgenic Mice”, Sun, J.; Ohkanda, J.; Coppola, D.; Yin, H.; Kothare, M.; Busiglio, B.; Hamilton, A. D.; Sebti, S. M.; Cancer Res. 2003, 63, 8922-8929. [Link]

2. “Design and Application of an Alpha-Helix-Mimetic Scaffold Based on an Oligoamide-Foldamer Strategy: Antagonism of the Bak BH3/ Bcl-x_L Complex”, Ernst, J.T.; Becerril, J.; Park, H. S.; Yin, H.; Hamilton, A. D.; Angew. Chem. Int. Edit. 2003, 42, 535-539. [Link][Faculty of 1000]   

1. “Development of a Potent Bcl-x_L Antagonist Based on Alpha-Helix Mimicry”, Kutzki, O.; Park, H. S.; Ernst, J. T.; Orner, B. P.; Yin, H.; Hamilton, A. D.; J. Am. Chem. Soc. 2002, 124, 11838-11839. [Link][Faculty of 1000]