37. "Multi-Tox: Application of the ToxR-Transcriptional Reporter Assay to the Study of Multi-Pass Protein Transmembrane Domain Oligomerization", Joce, C.; Wiener, A. A.; Yin, H.; Biochim. Biophys. Acta. 2011, 1808, 2948-2953. [Link]

36. "Development of Beta-Amino Alcohol Derivatives that Inhibit Toll-Like Receptor 4 Mediated Inflammatory Response as Potential Antiseptics", Chavez, S. A.; Martinko, A. J.; Lau, C.; Pham, M. N.; Cheng, K.; Mollnes, T. E.; Yin, H.; J. Med. Chem. 2011, 54, 4659-4669. [Link]

35. "Transmembrane Peptides Used to Investigate the Homo-Oligomeric Interface and Binding Hot-Spot of Latent Membrane Protein 1", Sammond, D. W.; Joce, C.; Takeshita, R.; McQuate, S.; Ghosh, N.; Martin, J. M.; Yin, H.; Biopolymers 2011, 95, 772-784. [Cover Article][Link]

34. "An MD2 Hot-Spot Mimicking Peptide that Suppresses TLR4-Mediated Inflammatory Response In Vitro and In Vivo", Liu, L. P.; Ghosh, N.; Slivka, P. F.; Fiorini, Z.; Hutchinson, M. R.; Watkins, L. R.; Yin, H.; ChemBioChem. 2011, 12, 1827-1831. [Cover Article][Link]

33. "Small Molecule Inhibitors of the TLR3/dsRNA Complex", Cheng, K.; Wang, X. H.; Yin, H.; J. Am. Chem. Soc. 2011, 133, 3764-3767. [Link]

32. "The BH3 Alpha-Helical Mimic BH3-M6 Disrupts Bcl-xL, Bcl-2, and Mcl-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-Dependent Manner", Kazi, A.; Sun, J.; Doi, K.; Sung, S. S.; Takahashi, Y.; Yin, H.; Rodriguez, J.; Becerril, J.; Berndt, N.; Hamilton, A. D.; Wang, H. G.; Sebti, S. M.; J. Biol. Chem. 2011, 286, 9382-9392. [Link]

31. "Transmembrane Domain Oligomerization Propensity Determined by ToxR Assay", Joce, C.; Wiener, A. A.; Yin, H.; J. Vis. Exp. 2011, 51, e2721. [Link]

30. “Selection, Preparation, and Evaluation of Small-Molecule Inhibitors of Toll-Like Receptor 4”, Bevan, D. E.; Martinko, A. J.; Loram, L. C.; Stahl, J. A.; Taylor, F. R.; Joshee, S.; Watkins, L. R; Yin, H.; ACS Med. Chem. Lett. 2010, 1, 194-198. [Link]

29. “Toll-Like Receptor 4 in CNS Pathologies”, Buchanan, M. M.; Hutchinson, M. R.; Watkins, L. R.; Yin, H.; J. Neurochem. 2010, 114, 13-27. [Link]

28. "Application of a Novel In Silico High Throughput Screen to Identify Selective Inhibitors for Protein-Protein Interactions", Joce, C.; Stahl, J. A.; Shridhar, M.; Hutchinson, M. R.; Watkins, L. R.; Fedichev, P. O.; Yin, H.; Bioorg. Med. Chem. Lett. 2010, 20, 5411-5413. [Link]

27. “Development of Agents That Modulate Protein-Protein Interactions in Membranes”, Zhao, T. X.; Martinko, A. J.; Le, V. H.; Zhao, J.; Yin, H.; Curr. Pharm. Des. 2010, 16, 1055-1062. [Link]

26. “Evidence that Tricyclic Small Molecules May Possess TLR 4 and MD-2 Activity”, Hutchinson, M. R.; Loram, L. C.; Zhang, Y.; Shridhar, M.; Rezvani, N.; Berkelhammer, D.; Phipps, S.; Foster, P. S.; Landgraf, K. E.; Falke, J. J.; Rice, K. C.; Maier, S. F.; Yin, H.; Watkins, L. R; Neurosci. 2010, 168, 551-563. [Link]

25. “Possible Involvement of Toll-Like Receptor 4/MD-2 Activity of Opioid Inactive Isomers Causes Spinal Proinflammation and Related Behavioral Consequences”, Hutchinson, M. R.; Lewis, S. S.; Coats, B. D.; Rezvani, N.; Zhang, Y.; Shridhar, M.; Wieseler, J.; Somogyi, A. A.; Yin, H.; Maier, S. F.; Rice, K. C.; Watkins, L. R. Neurosci. 2010, 167, 880-893 . [Link]

24. “Evidence that Opioids May Have Toll Like Receptor 4 and MD-2 Effects”, Hutchinson, M. R.; Zhang, Y.; Shridhar, M.; Evans, J. H.; Buchanan, M. M.; Zhao, T. X.; Slivka, P. F.; Coats, B. D.; Rezvani, N.; Wieseler, J.; Hughes, T. S.; Landgraf, K. E.; Chan, S.; Fong, S.; Phipps, S.; Falke, J. J.; Leinwand, L. A.; Maier, S. F.; Yin, H.; Rice, K. C.; Watkins, L. R.; Brain Behav. Immun. 2010, 24, 83-95. [Link]

23. “A Peptide Antagonist of the TLR4/MD2 Interaction”, Slivka, P. F.; Shridhar, M.; Lee, G. I.; Sammond, D. W.; Hutchinson, M. R.; Martinko, A. J.; Buchanan, M. M.; Sholar, P. W.; Kearney, J. J. Harrison, J. A.; Watkins, L. R.; Yin, H.; ChemBioChem 2009, 10, 645-649. [Link]

22. “Using Two Fluorescent Probes to Dissect the Binding, Insertion, and Dimerization Kinetics of a Model Membrane Peptide”, Tang, J.; Yin, H.; Qiu, J.; Tucker, M. J.; DeGrado, W. F;. Gai, F.; J. Am. Chem. Soc. 2009, 131, 3816-3817. [Link]

21. "Understanding Membrane Proteins. How to Design Inhibitors of Transmembrane Protein-Protein Interactions" in Protein Engineering (Köehrer, C.; RajBhandary, U. L. Ed.), Slusky, J. S; Yin, H.; DeGrado, W. F.; Springer Verlag, Nucl. Acids and Mol. Biol. 2009, 22, 315-338. [Link]

20. “Exogenous Agents that Target Transmembrane Domains of Proteins”, Yin, H.; Angew. Chem. Int. Edit. 2008, 47, 2744-2752. [Cover Article][Link]

19. “Computationally Designed Peptide Inhibitors of Protein-Protein Interactions in Membranes”, Caputo, G. A.; Litvinov, R. I.; Li, W.; Bennett, J. S.; DeGrado, W. F.; Yin, H.; Biochemistry 2008, 47, 8600-8606. [Link]

18. “Design, Synthesis, and Evaluation of Biotinylated Opioid Derivatives as Novel Probes to Study Opioid Pharamcology”, Li, Y.; Chase, A. R.; Slivka, P. F.; Baggett, C. T.; Zhao, T. X.; Yin, H.; Bioconjug. Chem. 2008, 19,2585-2589. [Link]

17. “Peptide Probes for Protein Transmembrane Domains”, Slivka, P. F.; Wong, J.; Caputo, G. A.; Yin, H.; ACS Chem. Biol. 2008, 3, 402-411.[Link][Introducing the Authors]