108. "Discovery of Small Molecules as Multi-TLR Agonists with Proinflammatory and Anticancer Activities", Zhang, L.; Dewan, V.; Yin, H.; J. Med. Chem. 2017, 60, 5029-5044. [Link]

107. "Updating the MISEV Minimal Requirements for Extracellular Vesicle Studies: Building Bridges to Reproducibility", Witwer, K. W.; Soekmadji, C.; Hill, A. F.; Wauben, M. H.; Buzás, E. I.; Di Vizio, D.; Falcon-Perez, J. M.; Gardiner, C.; Hochberg, F.; Kurochkin, I. V.; Lötvall, J.; Mathivanan, S.; Nieuwland, R.; Sahoo, S.; Tahara, H.; Torrecilhas, A. C.; Weaver, A. M.; Yin, H.; Zheng, L.; Gho, Y. S.; Quesenberry, P.; Théry, C.; J. Extracell. Vesicles 2017, 6, e1396823. [Link]

106. "A Polar SxxS Motif Drives Assembly of the Transmembrane Domains of Toll-Like Receptor 4", Kargas, K.; Marzinek, J.; Holdbrook, D.; Yin, H.; Ford, R.; Bond, P.; Biochim. Biophys. Acta. 2017, 1859, 2086-2095. [Link]

105. "Peptides Derived From MARCKS Block Coagulation Complex Assembly on Phosphatidylserine", Kastelowitz, N.; Tamura, R.; Onasoga, A.; Stalker, T. J.; White, O. R.; Brown, P. N.; Brodsky, G. L.; Brass, L. F.; Branchford, B. R.; Di Paola, J.; Yin, H.; Sci. Rep. 2017, 7, 4275. [Link][JTH What the Neighbors Say]

104. "Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles", Witwer, K. W.; Reiner, A. T.; van Balkom, B. W. M.; de Beer, J.; Brodie, C.; del Portillo, H. A.; Gabrielsson, A.; Gimona, M.; Ibrahim, A. G.; de Kleijn, D.; Lai, C. P.; Lener, T.; Lötvall, J.; Reischl, I. G.; Salomon, C.; Tahara, H.: Toh, W. S.; Wauben, M.; Yang, V. K.; Yeo, R. W. Y.; Yin, H.; Giebel, B.; Rohde, E.; Lim, S. K.; Stem Cell Transl. Med. 2017, 6, 1730-1739. [Link]

103. "NSAIDs are Caspase Inhibitors", Smith, C. E.; Soti, S.; Jones, T. A.; Nakagawa, A.; Xue, D.; Yin, H.; Cell Chem. Biol. 2017, 24, 281-292. [Link][C&EN Concentrates][NIH Research Matters][WebMD]

102. "Small Molecules an Peptides Recognizing Transmembrane Domains of Membrane Proteins", Zeng, X.; Wu, P.; Yao, C.; Liang, J.; Zhang, S.; Yin, H.; Biochemistry 2017, 56, 2076-2085. [Link]

101. "Endogenous TLR4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma", Bhattacharyya, S.; Midwood, K. S.; Yin, H.; Varga, J.; Adv. Would Care 2017, 6, 356-369. [Link]

100. "Computational Design of Membrane-Curvature Sensing Peptides" in Computational Protein Design (Samish, I. Ed.), de Jesus, A. J.; Yin, H.; Springer New York, Methods Mol. Biol. 2017, 1529, 417-437. [Link]

99. "Rationally Designed Peptide Probes for Extracellular Vesicles", Tamura, R.; Yin, H.; Adv. Clin. Chem. 2017, 79, 25-41. [Link]

98. "Polymer Based Purification of Exosomes" in Extracellular Vesicles: Methods and Protocols (Kuo, W. P.; Jia, S. Ed.), Brown, P. N.; Yin, H.; Springer Verlag, Methods Mol. Biol. 2017, 1660, 91-103. [Link]

97. "Supramolecular Membrane Chemistry" in Comprehensive Supramolecular Chemsitry II (Atwood, J. L. Ed.), de Jesus, A. J.; Yin, H.; Elsevier (Kidlington), 2017, 5, 311-328. [Link]

96. "HMGB-1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia", Das, N.; Dewan, V.; Grace, P. M.; Rosenfeld-Gunn, R. J.; Tamura, R.; Tzarum, N.; Watkins, L. R.; Wilson, I. A.; Yin, H.; Cell Rep. 2016, 17, 1128-1140. [Link]

95. "Drugging Membrane Protein Interactions", Yin, H.; Flynn, A. D.; Annu. Rev. Biomed. Eng. 2016, 18, 51-76. [Link]

94. "Determinants of Curvature Sensing Behavior for MARCKS-Fragment Peptides", de Jesus, A. J.; White, O. R.; Flynn, A. D.; Yin, H.; Biophys. J. 2016, 110, 1980-1992.[Link][BJ Homepage Feature]

93. "A Two-Hit Challenge Creates Persistent Neuropathic Pain Via Sustained Spinal Neuroinflammation: Morphine as Contributor to Chronic Pain", Grace, P. M.; Strand, K. A.; Galer, E. L.; Urban, D. J.; Wang, X.; Baratta, M. V.; Fabisiak, T. J.; Anderson, N. D.; Cheng, K.; Greene, L. I.; Berkelhammer, D.; Zhang, Y.; Ellis, A. L.; Yin, H.; Campeau, S.; Rice, K. C.; Roth, B. L.; Maier, S. F.; Watkins, L. R.; Proc. Natl. Acad. Sci. U. S. A. 2016, 113, E3441-E3450.[Link][Science Latest News]

92. "Directly Activating AlphaIIb-Beta3 Initiates Outside-In Signaling by Causing AlphaIIb-Beta3 Clustering", Fong, K. P.; Zhu, H.; Span, L. M.; Moore, D. T.; Tamura, R.; Yin, H.; DeGrado, W. F.; Bennett, J. S.; J. Biol. Chem. 2016, 291, 11706-11716.[Link]

91. "Evaluation of TLR4 Inhibitor, T5342126, in Modulation of Ethanol Drinking Behavior in Alcohol Dependent Mice", Bajo, M.; Montgomery, S. E.; Cates, L. N.; Nadav, T.; De Lucchi, A.; Cheng, K.; Yin, H.; Crawford, E. F.; Roberts, A. J.; Roberto, M.; Alcohol Alcohol. 2016, 51, 541-548.[Link]

90. "Lipid-Targeting Peptide Probes for Extracellular Vesicles", Flynn, A. D.; Yin, H.; J. Cell. Physiol. 2016, 231, 2327-2332.[Link]

89. "Chemical Biology Probes for Extracellular Vesicles Facilitates Studies of Neuroinflammation", Yan, L.; Liang, J.; Yin, H.; ACS Chem. Neurosci. 2016, 7, 418-419. [Link]

88. "Pyrimidine Triazole Thioether Derivatives as Novel TLR5/Flagellin Complex Inhibitors", Yan, L.; Liang, J.; Yao, C.; Wu, P.; Zeng, X.; Cheng, K.; Yin, H.; ChemMedChem 2016, 11, 822-826 (Selected as a Very Important Paper (VIP) for the Protein-Protein Interactions thematic issue). [Link]

87. "Pharmacological Characterization of the Opioid Inactive Isomers (+)-Naltrexone and (+)-Naloxone as Toll-Like Receptor 4 Antagonists", Wang, X.; Zhang, Y.; Peng, Y.; Hutchinson, M. R.; Rice, K.; Yin, H.; Watkins, L. R.; Br. J. Pharmacol. 2016, 173, 856-869. [Link]

86. "A Mitochondria-Targeted Ratiometric Two-Photon Fluorescent Probe for Biological Zinc Ions Detection", Ning, P.; Jiang, J.; Li, L.; Wang, S.; Yu, H.; Feng, Y.; Zhu, M.; Yin, H.; Guo, Q.; Meng, X.; Biosens. Bioelectron. 2016, 77, 921-927. [Link]

85. "Comparing Residue Clusters from Thermophilic and Mesophilic Enzymes Reveals Adaptive Mechanisms", Sammond, D. W.; Kastelowitz, N.; Himmel, M. E.; Yin, H.; Crowley, M. F.; Bomble, Y. J.; PLoS One 2016, 11, e0145848. [Link]

84. "Therapeutic Developments Targeting TLR4-Mediated Neuroinflammation", Li, J.; Csakai, A.; Jin, J.; Zhang, F.; Yin, H.; ChemMedChem 2016, 11, 154-165. [Link]

83. "Progress in Immunomodulators Targeting Toll-Like Receptors", Xu, Q.; Jiang, S.; Cheng, K.; Yin, H.; Prog. Pharm. Sci. 2016, 40, 42-55 . [Link]